Lyumjev

Arcane Lyumjev experiments

I’ve reported previously about my experiences with insulin timings, including what happens when we go off-label and blend Humalog U100 with Lyumjev U100. I’ve now done another phase of experimentation, with a new data point. And some analysis of why these results might come about. I’ll first rewind a bit and explain that Humalog / …

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Basal impacts of insulin speed

I’ve written numerous times about modelling the activity profiles of various insulins. Telling my oref-based Automated Insulin Delivery (AID) system which insulin I’m using lets it model the current situation (and forecast the future) quite well. We usually think about this in terms of the simple concept of a single bolus: how quickly it starts …

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Insulin timings (2022)

Different insulins have effect (and get used up) at different speeds, and modelling this is important for accurate calculation of subsequent insulin doses. Some automated insulin delivery (AID) systems try to determine this themselves (e.g. CamAPS has nowhere for us to tell it which insulin we’re using) and some (e.g. Medtronic and Control-IQ) seem to …

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Hyperinsulinaemia

A long word that basically means “too much insulin in the blood”. Hyperinsulinaemia is especially associated with Type 2 Diabetes and insulin resistance, where the body’s response to insulin is reduced, and higher-than-normal insulin levels are needed to get the required effect. But it can apparently also be involved with Type 1 (allegedly not just …

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Mixing insulins – theory and practice

Faster insulins can be dramatically useful for AID (Automated Insulin Delivery) systems. Anything that reduces latency within the loop can improve our overall glycaemic control. A topic often discussed amongst people looking to get faster insulins is the possibility of mixing insulins in pumps. I do have to be clear and point out that this …

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